The Last of Us Part 2 Remastered: A Guide to Obtaining the Biology Lesson Trophy in No Return Mode

Biology Lesson is a newly introduced trophy in The Last of Us Part 2 Remastered: No Return. This feature was part of a recent update that also introduced new cosmetic items and additional playable characters for the game’s roguelike mode. Unlocking this trophy requires players to complete a run as Bill, utilizing a custom pump shotgun to successfully defeat a Bloater—a task that presents considerable challenges, as this ferocious infected variant is resilient and formidable.

This guide aims to provide comprehensive insights on how to effectively eliminate Bloaters to achieve the coveted trophy.

Steps to Unlock the Biology Lesson Trophy in The Last of Us Part 2 Remastered: No Return

Bill faces off against the menacing Bloater (Image via Sony Interactive Entertainment)
Bill faces off against the menacing Bloater (Image via Sony Interactive Entertainment)

The first step towards unlocking the Biology Lesson trophy is to unlock Bill in the No Return mode. Unlike other playable characters, Bill does not start with his custom shotgun readily available. To access this powerful weapon, players must complete a dead drop mission, where the shotgun can be found at a designated hideout. It’s important to remember that the rewards from these dead drops are generated randomly.

Though Bill’s shotgun is slightly upgraded compared to regular weapons, players should exercise caution with its limited ammunition supply while navigating the intense encounters in No Return. Once you procure the shotgun, wish for your run to feature one of the two available Bloater boss fights.

Effective Strategies for Securing the Biology Lesson Trophy

No Return allows for great flexibility in customizing gameplay settings. Players can tailor their runs by selecting specific enemy factions, adjusting game modifiers, and removing various challenges. It is advisable to eliminate all other boss encounters except for the garage or arcade Bloater to increase your chances of a successful fight.

Although the drop rate for the custom pump shotgun is low, there is a slight possibility of acquiring it earlier when playing on the Grounded difficulty level, which is the game’s most challenging setting. Dead drops can only be encountered in the following challenge modes:

  • Hunted
  • Holdout
  • Assault

For increased odds of encountering dead drops, consider removing the Capture objective from your selected challenges. It’s essential to note that using cheats or gameplay modifiers will not aid your progress; the system will disregard achievements made under these altered conditions.

Players who feel their aiming skills need refinement should enhance their aim assist sensitivity or activate target lock to ensure clearer shots. Precision is key in this challenge, although Bloaters are substantial targets that are easier to hit. While it’s necessary to defeat a Bloater specifically using Bill’s custom shotgun, players can chip away at its extensive health bar using other weapons, like pipe bombs or trap mines, before delivering the final blow with the shotgun.

Conserving ammunition is critical since the pump shotgun can only store up to eight shells, with six in the chamber. If you happen to receive a FEDRA flamethrower from dead drops, deploying it can be highly effective, as fire is a significant weakness for these infected foes. Bloaters have been present in the post-apocalyptic world longer than most, resulting in their evolution into aggressive creatures with toughened defense.

Be mindful that excessive use of the custom pump shotgun may lead to rapid ammunition depletion. Strategically timing shots while employing alternative items can enhance your chances of victory.

The garage Bloater's arena facilitates easier maneuvering (Image via Sony Interactive Entertainment || Sportskeeda Gaming)
The garage Bloater’s arena facilitates easier maneuvering (Image via Sony Interactive Entertainment || Sportskeeda Gaming)

Once the Bloater’s health is critically low, unleash your custom pump shotgun to finish the job. Upon defeating the Bloater, the Biology Lesson trophy will promptly unlock, allowing you to clear out any remaining infected in the vicinity to complete your run.

The Last of Us Part 2 is currently available on PlayStation 4, PlayStation 5, and PC.

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