Lazarus made its debut with episode 1 on April 6, 2025, grabbing significant attention as a new work by the acclaimed Shinichiro Watanabe, best known for his iconic series, *Cowboy Bebop*. The animation is brought to life by the esteemed Studio MAPPA, known for its high-quality productions. This inaugural episode introduces viewers to a formidable threat posed by Dr. Skinner’s controversial drug, Hapna, and centers around two pivotal characters: Dr. Skinner and Axel Gilberto.
The plot unfolds in a world where Dr. Skinner’s Hapna has seemingly resolved the majority of humankind’s health crises. However, the narrative quickly reveals dire consequences associated with the drug. Hersch, a mysterious figure, is on a mission to locate Dr. Skinner, enlisting the help of Axel, a convict with a troubled past. Despite considering the offer, Axel opts for an escape from prison, setting the stage for thrilling developments.
Unveiling the Truth: The Impact of Dr. Skinner’s Actions

The episode opens with a brief overview of Dr. Skinner’s revolutionary yet perilous drug, Hapna, designed to eliminate diseases. The narrative quickly shifts to present-day events where Hersch visits Axel in prison, showing him a shocking video featuring Dr. Skinner. This video alerts the public to Hayna’s devastating side effects, raising alarms about impending fatalities. In this context, viewers are introduced to a diverse cast of characters, including Douglas Harding, Christine, Leland, and Elaina, each reacting to the alarming news.
During their meeting, Hersch proposes a collaboration with Axel to capture Dr. Skinner. Despite her offer, Axel chooses the path of defiance, initiating a plan for his escape. He successfully breaks free, prompting Hersch to inform Douglas of his newfound freedom and their urgent mission to bring him back.
Axel’s Dangerous Escape: The Chase Begins

The second act of *Lazarus* episode 1 highlights Axel, still in his prison garb, as he eludes capture by masquerading in front of a police officer. Once he secures a change of clothing, a series of high-octane chase sequences ensues, showcasing his agility and resourcefulness. As he navigates through trains and over rooftops, viewers witness Axel’s incredible acrobatic skills in action.
Just when it seems he has reached a dead end with Douglas in pursuit, Axel takes a daring leap, surviving a perilous fall by utilizing one of the advanced aerial machines tracking him. Unfortunately, Christine soon finds him, leading to a showdown that results in Axel being subdued. He regains consciousness in a barber shop, surrounded by Hersch and her team, who welcome him to the Lazarus organization.
Conclusion: Setting the Stage for Future Adventures
The first episode of *Lazarus* adeptly established the narrative’s foundation while providing a thrilling introduction to Axel Gilberto as the lead character. As the series progresses, viewers can anticipate the forthcoming adventures of the Lazarus team as they embark on their inaugural mission.