In the realm of Last Epoch, the Twisted Heart of Uhkeiros emerges as a formidable and coveted unique relic. This item is particularly valued within builds that emphasize substantial health pools and defensive scaling. Its unique property allows players to convert a portion of their life into ward—a crucial protective buffer—enabling a dynamic risk-reward play style that appeals to both hybrid and tank-oriented characters.
This guide aims to delve into the distinctive affixes associated with the Twisted Heart of Uhkeiros, identify where players can obtain it, and discuss the builds that can gain the most advantage from its unique mechanics.
Why is the Twisted Heart of Uhkeiros Exceptional?
Distinguished from standard relics in Last Epoch, the Twisted Heart of Uhkeiros enables the conversion of a fraction of current health into ward, merging offensive capabilities with a defensive shield during spellcasting. This innovative design fosters a compelling synergy between resilience and aggression.

Unique Modifiers of the Twisted Heart of Uhkeiros:
- (5% to 8%) of Current Health converted to Ward when casting a Necrotic Spell
- (5% to 8%) of Current Health converted to Ward when casting an Elemental Spell
- +1 to Level of Necrotic Spell Skills
- +1 to Level of Elemental Spell Skills
- +(10 to 16) Strength (Enhances armor by 4% per point and improves strength-based skills)
- (10% to 16%) increased Cast Speed (Allows for a higher frequency of skill casting)
This relic is particularly synergistic for classes that utilize health-costing skills or thrive on both Strength and health scaling. The ward generation aspect fosters a robust defense that rewards astute and calculated offensive strategies.
How to Obtain the Twisted Heart of Uhkeiros in Last Epoch
Unlike items available through random world drops, the Twisted Heart of Uhkeiros is linked to a specific boss encounter. Players must deliberately engage with targeted content to secure this relic.

Source of Drops
- Boss: Emperor of Corpses (6% base drop chance, potentially up to 48% with increased item rarity)
- Timeline: Reign of Dragons (found within the Monolith of Fate system at Level 85)
- Corruption Requirement: This item drops exclusively from the empowered version of the timeline when the timeline corruption level is at least 200.
To summon the Emperor of Corpses, players must complete the quests: Drowned Thetima, Island Battlefield, and Eye of the Storm in the Reign of Dragons area. Note that you must finish the initial two quests and maintain appropriate Stability levels (400 in Normal mode and 850 in Empowered mode) to initiate this quest.

Effective Farming Strategies
- Enhance Timeline Stability: Aim to complete echoes swiftly for more frequent access to the Emperor of Corpses fight.
- Increase Corruption: Utilize Beacons and eliminate the Shade of Orobyss to gradually elevate your corruption level.
- Leverage Echo Rewards: Focus on echoes that provide “Unique or Set Relic”rewards to potentially increase your drop chances.
- Blessings for Enhancement: Equip blessings that enhance your unique item or relic drop rate.
Implementing these targeted farming strategies is critical, given that the Twisted Heart will not appear through any other means in Last Epoch.
Optimal Builds Featuring the Twisted Heart of Uhkeiros
Thanks to its unique mechanic of ward generation through health expenditure, this relic is particularly effective in builds that use life as a resource for skill casting or that maintain substantial health pools for ward accumulation.
1) Lich (Caster Builds with Health Costs)
Liches are inherently designed to sacrifice health to utilize spells, making them ideal candidates for this relic. It synergizes exceptionally well with skills like Soul Feast, Death Seal, or Transplant.
2) Forge Guard (Strength-Focused Builds)
Forge Guards thrive on high strength scaling and resilience. The Twisted Heart not only enhances their strength but also ensures ward generation for additional survivability.
3) Void Knight (Hybrid Melee Tank Builds)
If your Void Knight employs health-draining abilities and stacks Strength, the Twisted Heart offers consistent ward to navigate challenging content effectively.
Overall, the Twisted Heart of Uhkeiros is not merely rare; it introduces a unique gameplay dynamic that few other items can match. Converting health into a protective shield allows players to explore innovative defensive strategies, especially for characters that willingly exchange HP for power.
Whether you are tackling empowered Monoliths or preparing for high-corruption farming, this relic can be central to an aggressive yet resilient build that excels under pressure. To fully harness its potential, ensure your corruption levels are high, your health is topped off, and your build is finely tuned. You just might discover the heart that drives ward-based excellence.
If you’re searching to elevate your survivability without sacrificing your raw power, the Twisted Heart of Uhkeiros deserves a coveted spot in your gear setup. Although its acquisition method is stringent and its requirements are demanding, the reward is a distinctive item that can transform your endgame strategy in Last Epoch.