Fans enchanted by the intricate political intrigues, rich historical backdrop, and the sharp-witted protagonist of The Apothecary Diaries can take comfort in knowing they are not alone. This remarkable anime intertwines medical mysteries, court drama, and a character-driven narrative, creating a unique viewing experience. The show’s emphasis on its clever lead, Maomao, as she navigates the complexities of court life while unearthing secrets, has ignited a desire among audiences for more stories that resonate with its distinct flair.
Fortunately, the anime realm is brimming with series that echo the enchanting spirit of The Apothecary Diaries. With nuanced historical settings, empowered female characters, emotional depth, and a delightful blend of mystery and fantasy, there are numerous exceptional anime series waiting to captivate fans seeking similar charm. By exploring these recommendations, viewers might just uncover a new favorite series that enthralls them.
10 Dahlia in Bloom: Crafting a Fresh Start with Magical Tools
Anime Series by Typhoon Graphics; Based on the Light Novel by Hisaya Amagishi
Dahlia in Bloom tells the heartwarming tale of a talented magical toolmaker named Dahlia, who embarks on a journey to redefine her life following a failed engagement. Set in a fantastical world inspired by European aesthetics, the series delves into themes of self-discovery, resilience, and empowerment. Dahlia’s narrative of personal and professional development is particularly resonant for those who found inspiration in Maomao’s character arc.
While Dahlia in Bloom may lack the court intrigue found in The Apothecary Diaries, it compensates with its introspective tone and a protagonist who embodies intelligence and craftsmanship over sheer strength. Viewers who are drawn to strong female leads navigating their destinies with determination and skill will find that Dahlia’s journey is a compelling follow-up to Maomao’s story.
9 Spice and Wolf: THE MERCHANT MEETS THE WISE WOLF
Anime Series by Passione; Based on the Light Novel by Isuna Hasekura
Bringing together elements of economics and romance, Spice and Wolf narrates the adventures of Kraft Lawrence, a merchant, and Holo, a clever wolf deity. Their evolving partnership through trade and stimulating dialogues showcases a similar charm to The Apothecary Diaries.
Much like Maomao, Holo embodies intelligence and complexity, often outsmarting those around her. The rich historical context combined with an intricate portrayal of relationships is sure to attract fans who enjoyed the clever dynamics and undercurrents in The Apothecary Diaries. As one of the most acclaimed anime series, Spice and Wolf is an essential watch for any anime aficionado.
8 My Happy Marriage
Anime Series by Kinema Citrus; Based on the Light Novel by Akumi Agitogi
Set against an alternate Meiji-era Japan, My Happy Marriage features Miyo Saimori, a girl from a family with supernatural abilities who faces arranged marriage to a seemingly emotionless military officer. The series thoughtfully balances romance with themes of trauma, self-worth, and reconciliation, reminiscent of the emotional complexities in The Apothecary Diaries.
While it emphasizes romance and supernatural elements, the slow-burning narrative and character growth reflect Maomao’s transformation from a stoic individual to a more open and emotionally aware person. Its historical setting and focus on personal strength make it a great recommendation for viewers who appreciate stories of women asserting their identities against societal expectations.
7 Nina the Starry Bride
Anime Series by Signal.MD; Based on the Manga by Rikachi
Nina the Starry Bride follows Nina, an orphan who is trained to impersonate a deceased princess. This role thrusts her into a world of palace politics and royal intrigue, creating a suspenseful narrative filled with secrets and identity struggles. The love triangle involving Nina and two princes adds another layer of excitement, evoking the intricate relationships seen in The Apothecary Diaries.
Nina’s intelligence and adaptability amidst danger draw parallels to Maomao’s story, showcasing strong female characters navigating perilous political landscapes. Viewers intrigued by complex narratives involving courage and deception will find Nina the Starry Bride to be a rich and rewarding viewing experience.
6 Frieren: Beyond Journey’s End
Anime Series by Madhouse; Based on the Manga by Kanehito Yamada and Tsukasa Abe
In Frieren: Beyond Journey’s End, the story explores the aftermath of the hero’s journey through the eyes of Frieren, an elf mage who embarks on a reflective odyssey through a world that has moved beyond her triumphs. The emotional depth and measured storytelling present in this series will likely appeal to fans of The Apothecary Diaries.
Though it lacks the political drama inherent in Maomao’s world, it emphasizes personal growth and thoughtful pacing, methodically addressing themes of grief, memory, and purpose in a poignant manner that is rare in anime.
5 YATAGARASU: The Raven Does Not Choose Its Master
Anime Series by Pierrot; Based on the Novel by Chisato Abe
YATAGARASU: The Raven Does Not Choose Its Master immerses viewers in a world of Japanese mythology, where noble raven clans serve as protectors of the imperial family. The plot follows Yukiya, a young raven entangled in succession conflicts within the royal court, exploring political machinations that resonate with fans of The Apothecary Diaries.
The series presents a layered narrative of loyalty, betrayal, and tradition, with Yukiya showcasing the intelligence and discretion necessary for survival in a complex social hierarchy. Those who enjoy intrigue steeped in mythology and drama will find this series to be a compelling exploration of power dynamics.
4 Ascendance of a Bookworm
Anime Series by Ajia-do Animation Works; Based on the Light Novel by Miya Kazuki
In Ascendance of a Bookworm, the protagonist Myne is reincarnated in a medieval world where books are a rarity for the privileged. Driven to make literacy accessible to all, she faces significant obstacles as she attempts to print her own books. Similar to Maomao, Myne is resourceful and motivated by a love for knowledge that sets her apart in a rigid social structure.
The focus on detailed world-building and innovative elements in both series highlights clever female protagonists who challenge societal norms through intellect and creativity. If fans appreciated Maomao’s smart solutions, they will also be captivated by Myne’s journey and innovations in Ascendance of a Bookworm.
3 Yona of the Dawn
Anime Series by Pierrot; Based on the Manga by Mizuho Kusanagi
In this thrilling historical fantasy, Yona of the Dawn follows the journey of Princess Yona, whose sheltered existence is shattered by a coup. Forced into exile, Yona transforms from a naive royal into a powerful leader, making her narrative relatable to those who admired Maomao’s strength and ability to endure challenges.
Fans seeking an action-packed yet emotionally rich story with a strong female lead will find Yona of the Dawn an exhilarating transition from The Apothecary Diaries. The series delves into themes of justice and empowerment, offering a compelling mix of action and character development that echoes the depth of The Apothecary Diaries.
2 Raven of the Inner Palace
Anime Series by Bandai Namco Pictures; Based on the Novel by Kōko Shirakawa
Set against a backdrop of superstition and secrecy, Raven of the Inner Palace presents the enigmatic Raven Consort, who is responsible for mystical rituals and solving the emperor’s dilemmas. This series elegantly marries historical fantasy with supernatural mystery, akin to the court drama and investigative elements found in The Apothecary Diaries.
With stunning visuals and a palpable sense of tension, the series showcases the isolation and quiet strength of its female lead. Much like Maomao, the Raven Consort is astute and unafraid to defy authority in pursuit of justice. For fans who enjoyed the behind-the-scenes intrigue in The Apothecary Diaries, this anime is an excellent, spiritually aligned option.
1 Snow White with the Red Hair
Anime Series by Bones; Based on the Manga by Sorata Akiduki





Snow White with the Red Hair centers on Shirayuki, a skilled herbalist who captures a prince’s attention after fleeing her home to evade an unwanted romantic pursuit. This series artfully explores themes of agency, professional growth, and romance, all set against a captivating courtly backdrop. Its rhythmic pacing and the determined heroine mirror the elements that make The Apothecary Diaries so appealing.
While the romance is more pronounced, the series also examines political dynamics, class disparities, and the delicate balance between personal desires and duties. Shirayuki’s path as a court herbalist closely parallels Maomao’s journey, making it an absolute must-watch for those seeking another uplifting narrative of a woman carving out her place in a complex world after finishing The Apothecary Diaries.