Players grappling with the laboratory puzzle in Blue Prince will find an intriguing challenge awaiting them. Each day, new mysteries unfold within Mt. Holly manor, where the floor plan shifts, adding a unique twist to every visit. This guide offers detailed insights into solving the laboratory puzzle effectively.
Cracking the Laboratory Puzzle in Blue Prince
Upon entering the laboratory, you will encounter a puzzle split into two primary components. The first part focuses on the periodic table, requiring you to locate specific items scattered across the room. The second part centers around operating a machine that can only be activated once you’ve deciphered the clues from the periodic table puzzle.

Understanding the Periodic Table
You’ll find the periodic table displayed above the laboratory’s workbench, alongside a microscope and test tube stand. At the opposite end of the room, a bulletin board holds the essential code sheet relevant to the puzzle, conveniently positioned next to the lever machine.

To unveil the secret code, refer to the typical periodic table and document the elements in the order they appear on the code sheet. For instance, the first element, Plutonium, is designated by the number 1. Your aim is to gather the element symbols listed on the sheet.
Arranging these symbols into a coherent English phrase reveals the answer: Pu S H Th Re Eu Pa F Te Rn I Ne. With careful manipulation of the spaces, it translates to the instruction: Push Three Up After Nine.

Activating the Lever Machine
Next, approach the lever machine, which features levers labeled from 1 to 10. Following the solution derived from the puzzle, you need to first push up lever number 9, followed by lever number 3. This action will unlock the Blackbridge Grotto, a new area located in a cavern near the mansion, offering daily remote access to an extra terminal.
Essential Tips for the Laboratory Puzzle
The operation of the lever machine is contingent on its power supply. To enable this, you must connect a boiler room to the laboratory. There are two effective methods for accomplishing this:
- Utilizing the ceiling ducts to channel steam into any connected room that is equipped for it.
- Creating a direct link between a boiler room and the laboratory itself.

Once you have successfully powered the laboratory, the lever machine can be engaged, resulting in the introduction of a permanent feature in the game: the Blackbridge Grotto.