Devil May Cry 5: Complete Mission Guide and List

Gamers embarking on their journey through Devil May Cry 5 will encounter a total of 21 main missions. These quests follow the intertwined narratives of Dante, Nero, and V as they confront the formidable Demon Urizen and the ominous Qliphoth Tree. From the bustling streets of Redgrave City to the treacherous depths of the Qliphoth, players will have plenty of territory to explore.

In addition to the primary missions, players can discover 12 secret missions that are cleverly hidden behind portals within the main storyline. Completing these secret tasks rewards players with blue orb fragments, essential for boosting their health. Furthermore, players can earn a coveted gold orb upon successfully completing these missions with Vergil after having already cleared them with Dante, Nero, or V.

Comprehensive Overview of Main Missions in Devil May Cry 5

Prologue

Vergil uses Judgement Cut on some enemies.

The Prologue invites players to traverse the interior of the Qliphoth as Nero, culminating in an anticipated showdown with Urizen, which is intentionally designed for players to lose. However, skilled players may emerge victorious, unfolding a humorous alternate conclusion.

Mission 01: Nero

Nero Devil May Cry 5

Nero, equipped with his new Devil Breaker arms, embarks on a journey across a damaged bridge into Redgrave City. The mission culminates in an intense battle against the Qliphoth Roots, where players must strike the prominent blood clot at its core for damage.

Mission 02: Qliphoth

Continuing his adventure, Nero weaves through city streets and takes a shortcut through a hotel, leading to a dramatic confrontation with the colossal Goliath, a melee-focused boss.

Mission 03: Flying Hunter

Devil May Cry 5_Artemis

Navigating deeper into the city, Nero encounters the flooded areas and sewer systems before facing off against the lethal Death Scissors. The mission concludes with a duel against Artemis, a demon adept in long-range attacks.

Mission 04: V

Switching perspectives, players take control of V, who utilizes three familiars inspired by prior Devil May Cry bosses. Serving as a gameplay tutorial for V, this segment challenges players with a final encounter against Nidhogg, a formidable demon that resides within the Qliphoth Roots.

Mission 05: The Devil Sword Sparda

V’s journey continues underground, where he must confront the Elder Geryon Knight while uncovering valuable insights about the legendary Devil Sword Sparda.

Mission 06: Steel Impact

Devil May Cry 5_Gilgamesh

In this boss-specific stage, players control Nero as he goes up against Gilgamesh, the formidable metal demon that previously forced V into hiding.

Mission 07: United Front

Players can choose between V and Nero to traverse the devastated city. Each character follows a unique route before converging for a climactic battle against Proto Angelo and Scudo Angelo.

Mission 08: Demon King

Nero returns to the Qliphoth Tree for an anticipated rematch with Urizen. Players must battle their way back to the boss chamber, aiming to shatter Urizen’s protective crystal, though the fight is still designed for loss. An outright victory here leads to a distinct ending.

Mission 09: Genesis

Devil May Cry 5

Simultaneously occurring with the previous mission, players guide V in search of Dante and the Devil Sword Sparda, facing a trio of demon adversaries known as “Nobodies”in the concluding battle.

Mission 10: Awaken

Now stepping into Dante’s shoes, players experience the game’s opening from his perspective. After mastering Dante’s combat style, he encounters Urizen once more. This mission does not feature secret endings but concludes once the crystal is destroyed or after 30 seconds has elapsed.

Mission 11: Reason

Dante awakens from his slumber, carving a path through Redgrave City toward Cavaliere Angelo.

Mission 12: Yamato

Devil May Cry 5 Urizen

In this mission, Dante navigates to his childhood home, progressing toward the Qliphoth Tree. Upon arrival and unlocking a new ability, he faces Urizen yet again.

Mission 13: Three Warriors

Select any of the three protagonists to descend further into the Qliphoth, participating in numerous arena battles without a designated boss fight at the mission’s end.

Mission 14: Diverging Point: V

In V’s concluding mission, he confronts three prior bosses: Goliath, Artemis, and Cavaliere Angelo. V must recover his familiars one at a time, making it crucial to reclaim Shadow early to unleash melee combinations.

Mission 15: Diverging Point: Nero

Devil May Cry 5_Mission 14

Nero continues his descent into the Qliphoth, eventually reuniting with V to face the cunning demon Malphas, a witch fused with avian features who employs magical abilities for unexpected strikes.

Mission 16: Diverging Point: Dante

In Dante’s segment, players traverse deeper into the Qliphoth for a grueling battle against King Cerberus, a formidable boss utilizing various elemental attacks.

Mission 17: Brothers

In this pivotal mission, Dante faces Urizen in a boss-only format. Players can fully deplete Urizen’s health bar this time, creating an exhilarating showdown as he demonstrates enhanced speed and strength.

Mission 18: Awakening

Devil May Cry 5_Qliphoth Tree

Following Vergil’s return, Dante navigates the upper branches of the Qliphoth while battling V’s familiars on his quest to reach his brother.

Mission 19: Vergil

In one of the game’s most thrilling encounters, Dante goes head-to-head with Vergil, testing players’ skills against a fast and tactical opponent. In Vergil Mode, the roles reverse with Vergil battling Dante.

Mission 20: True Power

The game’s climax sees Nero engage his father in a final battle, pitting his abilities against Vergil’s rapid combat style. Alternatively, Vergil faces Dante, who now boasts the full arsenal of his weapons, including the Sin Devil Trigger.

Exploring All Secret Missions in Devil May Cry 5

Devil May Cry 5_Prologue

Secret Mission 01 – Eliminate all of the demons

Located in the hotel during Mission 2, this introductory secret mission teaches players the mechanics of the Secret Mission System. Clearing this task requires defeating all demons, a relatively easy challenge compared to later missions.

Secret Mission 02 – Don’t let any Red Empusa escape!

In the underground tunnels of Mission 3, players must hunt down every Red Empusa before they can flee. Timing your attacks is crucial to interrupt their escape animations.

Secret Mission 03 – Collect all of the Red Orbs

Devil May Cry 5_V 2

In Mission 4, players must collect red orbs swiftly, best accomplished by riding Shadow, as it allows V to clear obstacles while pursuing orbs.

Secret Mission 04 – Eliminate all of the demons without taking a hit.

In Mission 5, this challenge requires players to defeat all enemies without sustaining damage. Utilizing V’s distance attacks will make it easier to dodge and counter.

Secret Mission 05 – Get to the goal without touching the ground.

Available during Mission 8, this platforming challenge utilizes rising platforms through lava. Timing and precision with grim grips will help navigate to the objective effectively.

Secret Mission 06 – Eliminate all of the demons in 20 seconds or less.

Devil May Cry 5_V Arrives

In Mission 9, players have 20 seconds to defeat all enemies. Using V’s Devil Trigger abilities strategically will significantly hasten the mission’s completion.

Secret Mission 07 – Aim for their weak point and take them down with a single bullet.

After the initial fight with hellbats in Mission 10, rush through a pulsating red door to discover this mission. The objective is to eliminate Death Scissors with a single shot by targeting their weak spot at the right moment.

Secret Mission 08 – Maintain an S Stylish Rank.

During Mission 11, players must achieve and maintain an S-Rank throughout the fight. Beginning with an air taunt can help establish a strong rank early in the battle.

Secret Mission 09 – Stay in the air for more than 15 seconds.

Dante

This mission can be found in Mission 12. Players must remain airborne for over 15 seconds using techniques like Enemy Step and various melee attacks.

Secret Mission 10 – Get to the goal without touching the ground.

Located after defeating the mirage bosses in Mission 14, players must retrace their steps to find this mission. Utilizing abilities like Promotion or Shadow’s speed can simplify reaching the goal.

Secret Mission 11 – Head straight for the goal!

In Mission 15, behind the first divinity statue lies a path leading to a blue orb. Players must reach the goal quickly, mastering platform navigation and timed inputs to succeed.

Secret Mission 12 – Collect a set amount of Red Orbs.

Image of Dante From Devil May Cry With The Faust Hat

The final secret mission appears in Mission 16, requiring players to accumulate 800 Red Orbs by defeating a single Empusa. Utilizing the Dr. Faust’s fully upgraded Set Hat skill can maximize orb collection efficiency.

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