The Apothecary Diaries may initially appear to be an unconventional choice for an anime hit. Unlike many mainstream series that lean heavily on shonen tropes or delve into elaborate sci-fi and fantasy realms, this particular show distinguishes itself through its immersive setting inspired by ancient China. Its protagonist, Maomao, also defies typical character archetypes—her motivations stem from a profound intrigue with herbal medicine rather than romance, contributing to a narrative that feels refreshingly original. As the second season airs alongside ongoing adaptations in light novels and manga, excitement for The Apothecary Diaries continues to surge.
In a recent interview featured in Japan’s Da Vinci magazine (as mentioned by keiuzuki on X), Natsu Hyūga, the creative mind behind The Apothecary Diaries, disclosed an interesting tidbit: she once contemplated concluding the story much sooner than anticipated. Hyūga initially envisioned wrapping things up by Volume 12 of the light novel series, at a pivotal moment when Maomao confronts her emotions regarding Jinshi.
Behind the Scenes: The Author of The Apothecary Diaries
Natsu Hyūga: Architect of a World Filled with Intrigue
Natsu Hyūga remains a private individual, choosing to keep details of her personal life out of the public eye, much like many Japanese creators. She first released The Apothecary Diaries online in 2011, quickly garnering a dedicated fanbase. Its success led to print publication and ultimately sparked multiple manga adaptations, culminating in the anime that debuted in October 2023.
Set against the backdrop of a fictional empire reflective of the Tang Dynasty—influenced by elements from the 16th to 19th centuries—The Apothecary Diaries follows the life of Maomao, a resourceful young apothecary from a pleasure district. After being kidnapped and thrust into the imperial harem, her knowledge of herbal remedies and poisons enables her to address various mysterious illnesses and fatalities within the palace walls.
Maomao’s keen insights soon captivate Jinshi, a powerful eunuch, who assigns her an unusual role as a food taster for a favored consort. As Maomao uncovers deeper layers of palace secrets, she finds herself increasingly enmeshed in the complex tapestry of political intrigue.
Natsu Hyūga: An Expansive Vision for the Series
Maomao’s Evolution: A Change in Direction

Hyūga elaborated in her recent interview, stating, “When Maomao started acknowledging her feelings for Jinshi, I initially thought that moment around Volume 12 could serve as the story’s conclusion. It could have offered a satisfying closure.” Nonetheless, Hyūga’s growing attachment to her characters inspired her to extend the narrative further. “As I continued, I felt compelled to explore her journey more.”
Pacing Challenges Loom for Hyūga
Navigating Narrative Uncertainty





Opting not to conclude the series at Volume 12 has proven advantageous for fans, albeit with accompanying challenges. As the anime unfolds, there are growing concerns regarding the availability of The Apothecary Diaries’ source material for future seasons. Although Hyūga continues to write the light novels, the anime’s current pace may soon align with the published content, prompting worries about production delays or reliance on filler episodes—both of which could disrupt the meticulously balanced tone and pacing of the narrative.
The adaptation must now walk a tightrope: remain true to Hyūga’s original material while upholding narrative energy. Straying too far from the established storyline risks alienating loyal viewers, while rushing ahead without the guidance of the light novels threatens to compromise the tale’s quality. For now, the team must harmonize ambition with patience to preserve the series’ distinctive allure.
As The Apothecary Diaries embarks on a new journey in its second season, the surrounding uncertainty enriches its allure. Despite its burgeoning popularity, Hyūga has candidly admitted she has no definitive plan for the story’s conclusion. This creative flexibility introduces an element of suspense that mirrors Maomao’s adventures, promising fans that each new chapter and episode will uncover unique revelations, shrouded in unpredictability.
Source: keiuzuki/X