House created a unique blend of medical intrigue, dark humor, and a protagonist who broke the mold of the traditional compassionate TV doctor. Dr. Gregory House was an exceptionally skilled diagnostician, which allowed the other characters to overlook his acerbic bedside manner and his functional drug addiction. This medical procedural thrived on moral ambiguities, with the show often presenting debates among team members about what constitutes ethical decision-making. Drawing inspiration from Sherlock Holmes, House was among the first modern medical dramas to introduce elements of mystery and deductive reasoning into its storytelling.
Whether it’s the captivating medical mysteries, the romantic subplots, or the rebellious spirit of its protagonist challenging hospital norms, anyone missing House will find satisfaction in the following series. These shows have been influenced by House, enhancing its legacy while incorporating familiar elements that fans adored.
10 St. Denis Medical (2024-Present)
This Medical Mockumentary Shows The Humor In Practicing Medicine
While House leans towards the drama with flashes of dark comedy, NBC’s St. Denis Medical offers a lighter take. Both series highlight that the practice of medicine transcends life-and-death choices, encompassing absurd, frustrating, and profoundly human moments characteristic of hospital life.
Unlike House, which centers around a singular, brilliant yet misanthropic doctor solving medical cases, St. Denis Medical presents an ensemble of well-meaning but flawed healthcare professionals navigating daily chaos with humor. Both shows underscore the need for humor in serious careers, whether through House’s sharp wit or the comedic antics in St. Denis. With its renewal for a second season, it’s clear audiences are drawn to this humorous portrayal of healthcare.
9 Doc (2025-Present)
Dr. Amy Larsen Is A Brilliant Diagnostician With A Brutal Bedside Manner
Fox’s Doc shares significant similarities with House, particularly in its approach to medical storytelling and the character of Dr. Amy Larsen. Before her accident, she exhibited a more abrasive personality akin to House. Both characters share an insatiable drive to tackle complex medical issues, often believing their perspective is superior, sometimes crossing lines to put their patients first as a means to also feed their egos.
Amy’s character is unorthodox and blunt, mirroring House’s willingness to delve deep to find answers. While House operated on a case-of-the-week basis, Doc intertwines overarching mysteries with emotional and romantic developments. Fans of House will likely appreciate Doc’s challenging medical decisions and Amy’s unyielding commitment to patient care, particularly as the unanswered questions from season one pave the way for an exciting second season.
8 The Good Doctor (2017-2024)
A More Humanistic Approach To A Doctor Who Sees Things Differently
The Good Doctor and House both revolve around brilliant doctors who navigate social norms in ways that ultimately lead to improved patient outcomes. Freddie Highmore’s Dr. Shaun Murphy exhibits a communication barrier due to his autism, while House’s prickly persona stems from a conscious choice. Created by David Shore, who also developed House, the series explores similar themes, resulting in a successful run with 126 episodes over seven seasons.
In some respects, The Good Doctor acts as an emotional counterpoint to House: Shaun is empathetic and well-meaning but still makes social errors, while House is often cynical and deliberately difficult. Nonetheless, both characters challenge the medical establishment and possess extraordinary gifts that allow for exceptions in their treatment, solving cases that others cannot due to their unique perspectives.
7 Mary Kills People (2017-2019)
An ER Doctor By Day Provides Assisted Suicides At Night
Mary Kills People delves into morally complex medical issues, mirroring House’s examination of the ethical quandaries within healthcare. The protagonist, Dr. Mary Harris, works as an ER doctor while clandestinely assisting with suicides, an act driven by compassion yet entangled in legality. Given House’s disdain for bureaucracy and preference for logic, he might endorse Mary’s challenge against the system.
The series holds a 100% rating on Rotten Tomatoes. Both characters prioritize their sense of morality over legalities, exposing themselves to significant personal risk in pursuit of what they believe to be just. This Canadian series, consisting of only 18 episodes, presents a sharp, ethically nuanced narrative that explores the boundaries of medical care, resonating with themes from House.
6 New Amsterdam (2018-2023)
Dr. Max Wants To Tear Down Hospital Bureaucracy To Provide Better Care
New Amsterdam and House both critique the flaws within the medical system, albeit from different perspectives. Dr. Max Goodwin resonates with House in his willingness to flout regulations to prioritize patient care, yet while House’s approach stems from intellectual defiance, Max embodies optimism and a desire for reform, inspired by the real-life story of Eric Manheimer. His goal of eliminating bureaucracy to foster patient-centered care aligns with House’s belief that procedural red tape can obstruct quality medical practice.
Though New Amsterdam carries a more hopeful, emotionally uplifting tone, it still caters to viewers seeking medical dramas that challenge standard hospital practices. With five seasons under its belt, the series offers a dynamic, passionate take on transforming healthcare.
5 The Pitt (2025-Present)
If You Liked The Diagnostic Procedures In House, The Pitt Ups The Medical Gore
The Pitt presents a visceral and realistic depiction of emergency room life, making it an ideal follow-up for fans who appreciated House’s medical authenticity, irrespective of how bizarre the cases became. Where House often employed puzzle-like diagnostics, The Pitt emphasizes realism, reflecting the frenetic pace prevalent in emergency situations.
This series employs a real-time storytelling format reminiscent of 24, evoking memories of House’s unique episodes, like “5 to 9,”which shadowed Dr. Cuddy’s relentless day managing the hospital. By pulling viewers into the immediate, intense trials faced by medical professionals, The Pitt delivers an immersive and authentic experience, paralleling House’s dedication to illustrating the triumphs and tribulations of medicine. With its first season underway and already a hit for Max, The Pitt has been renewed for a second season.
4 Pure Genius (2016-2017)
A Maverick Surgeon Partners With A Silicon Valley Billionaire To Fast Track Medical Advancements
Pure Genius embodies the spirit of innovation and challenges inherent in medical practice, similar to House. Centered around a tech billionaire and a maverick surgeon, this series aims to eliminate traditional healthcare barriers to prioritize patient outcomes. While House focused narrowly on diagnostics, Pure Genius explores futuristic medicine utilizing advanced technology that remains theoretical.
Both series intertwine drama with humor, but Pure Genius leans into a sci-fi realm, while House relied on a more cynical reality. Though Pure Genius aired for just one season, its ambitious narrative and commitment to medical innovation make it an interesting watch, especially for fans of House eager to see intelligent minds push the boundaries of healthcare.
3 The Resident (2018-2023)
Matt Czuchry’s Dr. Conrad Hawkins Breaks Rules To Help Patients Like House
If you admired House’s boundary-pushing antics for patient benefit, you’ll appreciate The Resident. Dr. Conrad Hawkins, played by Matt Czuchry, is a passionate physician who often contests hospital protocols to secure optimal care for his patients, regardless of the repercussions. Like House, Dr. Hawkins continually clashes with institutional interests and the impediments posed by bureaucracy.
This series balances high-stakes medical drama with romantic tensions and interpersonal dynamics, making it a compelling choice for fans who enjoy both the rich emotional layers and romantic storylines found in House, such as Chase and Cameron’s relationship.
2 Transplant (2020-2024)
A Refugee Starts Over From The Bottom As A Resident
Transplant and House both represent nuanced medical dramas that highlight the brilliance and resilience of unconventional doctors. House follows the story of a caustic, rule-breaking genius, while Transplant focuses on Dr. Bashir “Bash”Hamed, a compassionate Syrian refugee striving to rebuild his medical career from the ground up. While Bash’s narrative carries a more emotionally attuned, human-centered tone than House’s, both series delve into ethical dilemmas, complex cases, and the defiance of professional conventions.
This Canadian series completed a successful four-season run and is ideal for those who appreciate emotionally nuanced, character-driven medical narratives with a compelling procedural backbone. Bash’s unique background invites fresh perspectives on patient care, echoing House’s relentless quest for the truth.
1 Watson (2025-Present)
Watson Is More Explicitly A Sherlock Holmes Medical Mystery Adaptation Than House Was
Watson and House share clear connections through their inspiration from Sherlock Holmes, though Watson is more transparent about its ties, as Dr. John Watson is Sherlock’s actual former partner. This series adopts a case-of-the-week approach akin to House, characterized by fascinating medical mysteries solved in brilliant, often cryptic manners, aided by a carefully assembled team. Both programs highlight complex, emotionally reserved protagonists with a strong sense of justice, despite employing unconventional methods.
Moreover, Watson introduces an overarching mystery centered on Holmes’ antagonist, Moriarty, whose return and objectives inject ongoing tension into the storyline. Fans of House will recognize familiar patterns in Watson, especially with season 2 already confirmed and the current season airing weekly.